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KMID : 0043320100330121919
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Archives of Pharmacal Research
2010 Volume.33 No. 12 p.1919 ~ p.1926
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Synthesis and characterization of novel unnatural bichalcones
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Gurung Santosh K.
Kim Soo-Bae
Park Hae-Il
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Abstract
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Five bichalcones (5-1 ∼ 5-4, 9) were prepared by the reaction of biphenyl-4,4′-dicarbaldehyde (4) and 4,4′-dioxybenzaldehyde (8) with the respective acetophenone analogs via Claisen-Schmidt condensation and were then fully identified by 1H-NMR, 13C-NMR and mass analyses.
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KEYWORD
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Bichalcones, Chalcone dimers, Claisen-Schmidt condensation, Suzuki-Miyaura reaction, Stille reaction, Ullmann diaryl ether synthesis
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